Page 213 - 2025中醫藥與天然藥物聯合學術研討會-中醫藥與天然藥物的挑戰Ｘ機遇與未來大會手冊

PP-31

Formulation and characterization of sunscreen from Vietnamese herbal

extracts

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Duyen Thi My Huynh, Minh-Ngoc Thi Le, Minh Hau Nguyen, Chi Cong Bui, Quan
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Dinh Tran, Kim Lan Huynh, Long Trong Hoang Mai, Thanh Ngan Nguyen, Nhan Ho
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Trung Nguyen, Kim Tham Le, Tuong-Phung Kim Nguyen, Phuoc-Vinh Nguyen* ,2
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1 Faculty of Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho City, Vietnam
2 University of Health Sciences, Vietnam National University Ho Chi Minh City, Ho Chi Minh
City, Vietnam
* Email: npvinh@uhsvnu.edu.vn

Abstract
Sunscreen is a critical and effective solution for protecting human skin from harmful effects
of UV rays. Sunscreen, withherbal ingredients, is one of the most effective methods for the
prevention of skin cancer. This study was performed toscreen the UV protection property of
potential herbal extracts followed by formulations and quality assessments. Different herbal
extracts, including Mangifera indica L., Styphnolobium japonicum L., Folium psidii Guajava,
Lonicera japonica Thumb, Glycyrrhiza uralensis Fisch and Polypodium leucotomos were
investigated for their UV protection efficacy. Relevant herbal extracts were selected and
corresponding suncreen was formulated. The influence of hydroxyethyl cellulose ratio,
Tween80 ratio, and herbal extract ratio on appearance, pH, spreadability, physical stability, and
in vitro SPF were further assessed to find out the most appropriate formulation. The results
revealed that M. indica and S. japonicum extracts showed the best UV protection capacities, as
reflected by their highest UV protection indicator of 6.1401±0.1910 and 5.1149±0.0414,
respectively. The sunscreen formulations composed 0.6% hydroxyethyl cellulose, 2.0%
Tween80, and 0.04% herbal extract was found best. All finalized formulations met the required
qualities for sunscreen sensitivity and effectiveness and satisfied quality requirements for the
commercial sunscreen products.

Keywords: Herbal extracts; In vitro SPF; Sunscreen; Ultraviolet