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3.  Lin YS, Chen YC, Chen TE, Cheng ML, Lynn KS, Shah P, Chen JS, and

                       Huang RFS*. Probing folate-responsive and stage-sensitive  metabolomics
                       and transcriptional co expression network markers to predict prognosis of
                       non-small  cell  lung  cancer  patients.  Nutrients.  2022;15(1):3-26.


                   4.  Huang A, Huang SY, Shah P, Ku WC, Huang KT, Liu YF, Su CL, and Huang

                       RFS*. Suboptimal folic acid exposure rewires oncogenic  metabolism and
                       proteomics signatures to mediate human breast cancer malignancy. J Nutri
                       Biochem. 2022; 106: 109000-15.

                   5.  Chang TY, Wu CH, Chang CY, Lee FJ, Wang BW , Doong JY, Lin YS, Kuo
                       CS, and Huang RFS*. Optimal dietary intake composition of choline and
                       betaine is associated with minimized visceral obesity-related hepatic steatosis
                       in   a    case-control    study.    Nutrients.    2022;     14(2):    261-278.


                   6.  Huang KT, Shen YL, Lee CN, Chu KY, Ku WC, Liu CY, and Huang RFS*.
                       Using  differential  threshold  effects  of  individual  and  combined
                       periconceptional  methyl  donor  status  on  maternal  genomic  LINE-1  and

                       imprinted  H19  DNA  methylation  to  predict  birth  weight  variance  in  the
                       Taiwan  pregnancy-newborn  epigenetics  (TPNE)  cohort  study.  J  Nutr.
                       2020;150(1):108-117.
                   7.  Chen WJ, and Huang RFS*. Low folate stress reprograms cancer stem cell-
                       like potentials and bioenergetics metabolism through activation of mTOR

                       signaling pathway to promote in vitro invasion and in vivo tumorigenicity of
                       lung cancers. J Nutr Biochem. 2018;53:28-38.
                   8.  Cheng CP, Chen CH, Kuo CS, Kuo HT, Huang KT, Shan YL, Cheng CH,

                       and Huang RFS*. Dietary choline and folate relationships with serum hepatic
                       inflammatory  injury  markers  in  Taiwanese  adults.  Asia  Pac  J  Clin  Nutr.
                       2017;26(4):642-649.
                   9.  Feng HC, Lin JY, Hsu SH, Lan WY, Kuo CS, Tian YF, Sun DP, and Huang
                       RFS*. Low folate metabolic stress reprograms DNA methylation activated ‐

                       sonic hedgehog signaling to mediate cancer stem cell like signatures and ‐
                       invasive tumour stage specific malignancy of human colorectal cancers. Int
                       J Cancer 2017;141: 2537–2550.

















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